Inclusion Criteria:

1. Participants with suspected or histologically confirmed Stage IIA (> 4 cm) to IIIB (T3N2) non-small cell lung carcinoma (NSCLC) with disease that is considered resectable
2. No brain metastasis
3. Treatment-naive for NSCLC (no prior systemic anti-cancer treatment)
4. Ability to provide surgical or biopsy tumor tissue for biomarkers
5. Eastern Cooperative Oncology Group (ECOG) Performance Status of ≤ 1

Exclusion Criteria:

1. Participants with an active, known or suspected autoimmune disease
2. Any positive test for hepatitis B virus or hepatitis C virus or human immunodeficiency virus (HIV)
3. Any previous anti-cancer treatment including cytotoxic, IO treatment, targeted agents, or radiotherapy for NSCLC
4. Prior treatment with any anti-PD-1, anti-PD-L1, anti-PD-L2, or anti-CTLA-4 antibody, or any other antibody or drug specifically targeting T-cell co-stimulation or checkpoint pathways

Other protocol-defined inclusion/exclusion criteria apply